Variation of influenza vaccine and the virus
Posted on October 31, 2009
Filed Under H1N1 Prevention | Leave a Comment
Prior to the annual influenza epidemic season on the vulnerable populations at high risk of complications of vaccination is to reduce the harm of influenza (including the reduction of morbidity, complications of influenza-related hospitalization rates, mortality and socio-economic burden of influenza disease, etc.) the most effective way to .
In this regard, the Third Affiliated Hospital, Sun Yat-sen Department of Infectious Diseases, Associate Professor Chong Yutian come up with a new influenza vaccine (2004 ~ 2005) manual, I saw the instructions prominently marked “A / New Caledonia / 20 / 99 (H1N1) A / Fujian / 411/2002 (H3N2) B / Shanghai / 361/2002 “message.
Some reporters puzzled, Associate Professor Chong explained, this is the WHO recommendations to China in 2004 is likely the winter spring of 2005, the popular three kinds of influenza virus strains, the most recent vaccination was specific to these three virus strains produced.
And from 2003 to 2004, compared, H3N2 and B virus strains are mutated, so even if the previous year had been vaccinated with influenza vaccine, we should still re-vaccination.
Influenza vaccine production processes and other infectious diseases, vaccine production process are very different.
Is generally located at the monitoring stations around the world to the dissemination of the monitoring of influenza strain to predict possible epidemic strain that year, and then these results tell the vaccine manufacturers, factories overtime working towards them.
Domestic use of all manufacturers of influenza vaccine is recommended by the World Health Organization, the Chinese Ministry of Health and National Influenza Center production of the vaccine strains recognized.
Vaccine production process is racing against time, and there is no available vaccine in the coming year, so the higher cost of production of influenza vaccines.
The reporter learned from the mouth, Associate Professor Chong Yutian understand that each influenza vaccine cost about 90 yuan, the price of vaccines against infectious diseases be considered in the high side.
Influenza vaccine effective protection and vaccine strain similar to the incidence of infections caused by strains, because each strain has a variation of the popular, so also changes the composition of the vaccine, which matches with the epidemic strain, can be more effective in preventing influenza.
Composition of influenza vaccine changes every year, it is not a vaccine can be vaccinated once and for all.
As the composition of influenza vaccine will be based on the annual bulletin to update the World Health Organization, and the inoculation of influenza vaccine produced antibodies effective protection period of approximately one year, so influenza vaccine requires vaccination once a year.
If there is a pandemic, the current vaccine can not be prevented, only during a pandemic strains to a similar strain of the vaccine preparation can be prevented.
As a media report states: “Analysis of viruses and production of the vaccine is very time-consuming and laborious, the whole process a bit like guessing.” To reduce this forecast errors generally contain three kinds of influenza vaccine composition of influenza virus strains, so that can also deal three possible pandemic of influenza viruses.
If you look at the annual influenza vaccine statement, you will find the annual influenza vaccine composition is different.
However, experts say, even if the did not guess the composition of influenza strains, because of the flu vaccine inoculation could produce as part of cross-immunity, infection of influenza symptoms may be more light.
With regard to vaccination time, description, wrote: “As was the seasonal influenza occurs, it is recommended once a year influenza vaccine inoculation. Inoculated the beginning of the fall in temperate regions, tropical endemic in the area before the arrival of peak vaccination.”
To make it easier for readers to understand the meaning of this sentence, He Jianfeng, deputy chief physician in the Guangdong Province as an example to do the relevant explanation.
Influenza can occur throughout the year in Guangdong Province, according to provincial influenza surveillance showed that the province of influenza activity increased in March to 4 ~ July to enter the peak in August from the activities of waning.
Therefore, vaccination activities may start from the year in November, as a means of prevention of influenza the following year.
High-risk groups receive influenza vaccination every year in December the best time to next year in February, completed before the vaccination campaign in the Spring Festival.
Population and have not been vaccinated for influenza high-risk groups, such as influenza has become popular in the region, should still be vaccinated.
Vaccination in the influenza pandemic, at least the first 10 ~ 15 days to conduct.
The main recommendation of vaccination is now targeting high-risk populations, such as the relatively poor resistance to the elderly, children and patients suffering from chronic heart and lung disease patients.
In addition, the spread of influenza because of professional reasons people such as medical personnel, teachers, drivers, nursing homes, preschools and all kinds of service trades and so on.
Because influenza and SARS, bird flu is very similar to early symptoms, so some experts have suggested that influenza vaccination contribute to the latter two kinds of infectious diseases investigation.
But for eggs or other components of the vaccine allergy, Guillain-Barre syndrome patients, less than three months pregnant pregnant women (more than three months of pregnancy should be used with caution in pregnant women), there are acute febrile diseases, patients with exacerbation of chronic diseases, severe allergic persons should not receive influenza vaccination, children under 12 years of age can not use the whole virus inactivated vaccine.
Experts point out: Do not think that flu vaccination is equivalent to entering a “safe.”
Of all the vaccines against infectious diseases, only need an annual influenza vaccine inoculation time, last played this year have to fight this year, playing for next year have to shoot, prevention is a lifelong process, because it is based on the variation caused by influenza viruses.
Associate Professor Chong Yutian conducted an objective assessment of this: “If the flu virus mutation rate or larger than the experts expected, the effect of the vaccine may be compromised. Even so, the vaccine is still some effect, can alleviate the symptoms.”
From the Editor: The so-called “blessing in disguise, how can you know the non-fu”, in 2003, SARS and avian flu in 2004 gave rise to a serious threat to life and huge economic losses, but also awakened the sleeping in people’s heart health awareness and the awareness of prevention of infectious diseases.
While humans have not been able to effectively control the epidemic of influenza, but therapeutic drug, vaccine supply side, it should be made greater than the historical progress, from the prevention and control measures, too, have more than the historical experience of can reduce mortality.
Therefore, we have reason to believe that as long as we attach great importance to disease, we can overcome these problems.
General influenza vaccination in the upper arm of the deltoid, because, after all, is a foreign body, so after the influenza vaccine in some people or light or heavy can cause adverse reactions.
Small number of people can occur locally at the injection site redness, swelling, pain, ecchymosis, induration and so on, it was also fever, dizziness, chills, headache, sweating, muscle pain, joint pain and other systemic reactions.
In addition, there are few people appear itching, rashes and other skin reactions, other adverse reactions are quite rare.
These adverse reactions without treatment, usually disappears after a few days can be a natural.
If the symptoms continue for a long time, they should go to the hospital to check it.
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