H1N1 & pregnancy death rate
Posted on November 10, 2009
Filed Under H1N1 Prevention, H1N1 Symptoms & Diagnosis | Leave a Comment
New type of influenza H1N1 infection in pregnant women is expected to first be more than the typical symptoms of acute respiratory diseases (such as cough, sore throat, runny nose) and fever. Most pregnant women is based on a simple cold into the typical course of future conduct. However, in some pregnant women, pregnant female, can rapidly Deterioration of the disease may occur, including pneumonia and other complications of secondary bacterial infections. Pregnant women may also be due to the disease resulting in severe fetal distress. If suspected of being infected pregnant women, new-type influenza virus H1N1 should be tested, If the samples can not determine what kind of type-A influenza virus infection, samples should be sent to the Government into the public health sector conducted further tests to determine whether for the new H1N1 influenza virus infection.
Disposal of medical treatment and preventive medicine
On the current pandemic of H1N1 influenza virus, a new and effective drugs are the neuraminidase inhibitors (neuraminidase inhibitor) in the antiviral zanamivir (Relenza ®) and oseltamivir (Tamiflu ®), but the virus to the fund has just alkanes (adamantane ) anti-viral drugs such as amantadine (Symmetrel ®) and rimantadine (Flumadine ®) resistant. Any line with current case definition of pregnant women infected with,
Pipe is not confirmed, probable or suspected H1N1 influenza virus infection of new antiviral drugs, the experience should be accepted Therapy (empiric antiviral treatment). If there are close切pregnant women exposed to suspected or confirmed to be infected with H1N1 influenza virus, a new person should receive preventive drug treatment (chemoprophylaxis).
I voted for the proposal in line with zanamivir or oseltamivir treatment of drug cases, should pandemic flu symptoms started as soon as possible the emergence of healthcare processes, according to the case of seasonal flu pandemic such experience, symptoms appear within 48 hours of dosage effects best. However, some studies have indicated that some hospital patients occur even if the symptoms began to vote more than 48 hours after the drug is still beneficial. General recommendations of antiviral drugs to treat healthcare-way for five days, preventive drug treatment of the healthcare process to 10 days. Pregnant women using Oseltamivir and zanamivir, as well as preventive medicine and the general treatment of adults infected with flu pandemic similar to the proposed nature. If the antiviral drug sensitivity test results should be timely in accordance with changes in drug sensitivity of antiviral drugs given to pregnant women in treatment recommendations.
Influenza combined hyperthermia in pregnant women are known to cause adverse effects, studies have shown that mother’s body temperature is too high in the first pregnancy, fetal neural tube defect rate increased two-fold the machine, and the trading capacity of the merger or other birth defects, not good the production of results. Limited evidence suggests that: to give antipyretic drugs or vitamins containing leaves acid synthesis may be able to reduce this occurrence of fetal defects. Expectant mothers to newborns when the fever is the prognosis and the development of adverse risk factors, such as: neonatal spasticity, brain lesions, cerebral palsy, and neonatal deaths. Although it is difficult to distinguish is the impact of hyperthermia, or fever caused by the result of the cause, but because the mother of fetal body temperature is too high, not profit, so as long as the fever, pregnant women should receive treatment. Although the relevant research data is still not over, Acetaminophen, or fever during pregnancy drug of first choice.
Pregnancy is not a contraindication to use oseltamivir or zanamivir situation. Pregnant female may be due to a new H1N1 influenza infection and serious complications occur, therefore voted to zanamivir or oseltamivir drug treatment, or the benefits of preventive drug treatment over the use of antiviral agents during pregnancy risk. Oseltamivir and zanamivir during pregnancy and drug safety for the “C-class” drug that they have not entered clinical experiments conducted confirmed the safety of pregnant women in medicine. Do not know because of pandemic flu anti-viral agents for the mother and fetus on the safety of drugs, so oseltamivir or zanamivir assessed medication only in the embryonic and fetal risks than benefits would give.
Although some pregnant women report side effects after medication, however, affiliates of which has not yet been confirmed. Huai-pregnant female of the flu, to treat more inclined to use oseltamivir, because it can effect the body. Preventive drug treatment in the choice of the drug at present not clear, multi-recommended Zanamivir, because it will only be absorbed to a limited of the body, but the way the drug is inhaled dosage may cause respiratory complications, so have respiratory problems, pregnant women who used to be especially careful.
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